Pleased to meet you, we are Galapagos, a dynamic fast growing Biotech company. We’re in the business of changing lives.

Galapagos’ mission is to make a lasting positive contribution to society through discovery of innovative therapies for diseases with large unmet medical need. Galapagos seeks to develop a robust portfolio of therapies that have the potential to revolutionize existing treatment paradigms. The company’s ambition is to become a leading global biopharmaceutical company, focused on the discovery, development and commercialization of innovative medicines to improve patients’ lives. Galapagos’ historic focus on developing first-in-class medicines based on the discovery of novel targets in inflammation and fibrosis has led to the successful launch of our first medicine in rheumatoid arthritis in 2020 and in ulcerative colitis in 2021. The pivotal study in Crohn’s Disease is fully recruited and we expect topline data and potential approval in this new indication in a couple of years.

Galapagos is now entering an exciting new chapter to expand and diversify its pipeline for the future, starting with oncology, specifically CAR-T cell-therapy, a transformative treatment of different types of cancer. Through the combined acquisitions of CellPoint and AboundBio, we are propelling ourselves into next-generation cell therapies. CellPoint brings a novel, decentralized point-of-care cell therapy manufacturing model, which has the potential to offer efficient, 7-day time to treatment and avoids complex logistics, resulting in potential better patient outcomes and broader access. AboundBio’s cutting-edge fully human antibody-based platform provides access to a research engine for next generation multi-targeting CAR-Ts that have the potential to deliver deeper and durable clinical responses and that will be developed using CellPoint’s decentralized model.

We are looking for a Principal/Senior Scientist Statistical Modelling and Data Science - Mechelen,BE/Leiden,NL/Basel,CH

Scope

Our mission is to support drug development and post marketing through quantitative data analyses. We collaborate with medics, pharmacologists and epidemiologists to investigate clinical trial and real-world data providing scientific leadership and operational excellence. Our core business is the design and analysis of Phase 1-4 trials as well as accurate interpretation and communication of statistical results to support quantitative decision making.

Description

You will be responsible for:

• Implementation of innovative modelling and machine learning methods to clinical trial design and analysis.
• Acting as Study Biostatistician: Design and analysis of Clinical Pharmacology trials in healthy volunteers and Proof of Mechanism/Concept studies in patients (prior experience a plus).
• Predictive Modelling and Simulation efforts to provide answers to complex problems bridging research, development, medical and epidemiology.
• Gaining insight in the specific disease area and the competitive treatment landscape through focused literature search and summarizing of publicly available data.
• Stay current with relevant modelling and data science literature and EMA/FDA guidance.
• Help with infrastructure: R (Shiny, Stan, Mediana, SparkR etc.), python (NumPy, PyTorch, PySpark, Scikit-learn etc.), cloud computing (Docker, Kubernetes, big data, Databricks etc).
• Implement best practices in terms of modelling and data science to build confidence and adequately assess the reliability of statistical methods used.
• Engaging with external consultants and qualified CROs who help us.

Who are you?

• You have a PhD in computer science, statistics, epidemiology or related fields with experience in modelling and data science, preferentially in pharma or medical research.
• You are a pioneer who likes working in a rapidly evolving environment.
• You have experience building predictive models in an industrial setting and a good working knowledge of pro/cons of various approaches to reach impactful pragmatic solutions.
• A demonstrated track record of collaborating with colleagues outside your field of expertise. In particular experience in the biotech/pharma landscape (e.g. pharmacologists, MDs, epidemiologists, molecular biologists) would be a plus.
• Having the interest and ability to acquire in-depth knowledge of the disease area is a core skill. You are a keen learner with a desire to understand the full problem setting surrounding your task.
• Knowledge of the various aspects of clinical development and regulatory requirements is a plus.
• You have excellent written and oral communication skills and the ability to work in a multi-disciplinary environment. You are a team player and possess excellent interpersonal skills.

What’s in it for you ?

You will be part of an amazing company. As ‘make-it-happener’ you will get all the support you need to make your job successful. At Galapagos we aim to recruit the best people, who stand out among their peers, with integrity and excellent interpersonal and organizational skills. Our employees are the strength behind Galapagos, a highly motivated team, eager to maintain Galapagos’ leading position and achieve breakthroughs in pharmaceutical research. Galapagos offers a competitive remuneration package and a dynamic work environment.

We are Galapagos : together we can make it happen…!