Pharmacometrician Leader - Romainville, FR or Leiden, NL

Job description

 

Pleased to meet you, we are Galapagos, a dynamic fast growing biotech company with offices in Europe, in Belgium (Mechelen), France (Romainville), the Netherlands (Leiden), Switzerland (Basel) and in the US (Boston).

 

We’re in the business of changing lives. In our quest to discover and develop life-improving medicines we go where no one has ever gone before. In every challenge we face, we see new opportunities. We want to challenge the impossible. We need thought leaders and rapid thinkers, entrepreneurs in spirit and status quo-fighters. Collaborative innovators and perseverant idealists, we need the best-in-class. In other words, we need you: The ‘make-it-happeners’.

 

For our site in Romainville, France (alternatively Leiden, NL) we are looking for a Pharmacometrician Leader

 

Scope of the job

Within the Clinical Pharmacology department, you will apply quantitative approaches to develop and implement translational clinical pharmacokinetics and pharmacodynamics analysis to inform development of candidate molecules.

 

Your role

  • Promote the application of PBPK within the organization by identifying opportunities and liaising with all stakeholders
  • Manage the PBPK activities in close collaboration with Clinical Pharmacology Leaders and Pharmacometricians
  • Develop and execute PK and PD approaches, such as PBPK modelling, quantitative systems pharmacology, population PK and exposure response modelling and other model based analysis
  • Implement population PK, PK/PD modeling and simulation to assist in selection of doses for clinical development and/or clinical trial simulations
  • Communicate results of the analysis to a broader team (Clinical Development Team or Project Team)
  • Participate in preparing, reviewing and publishing scientific papers and abstracts

You will report to the Director Pharmacometrician Leader.

 

Job requirements

 

Who are you?

  • PhD or Master in Pharmacokinetics, Pharmacology or related field with a specific focus on pharmacokinetics and PK/PD modeling with at least 5 years’ experience in Clinical Development in Pharmaceutical Industry, Contract Research Organizations or academia
  • Hands-on experience with PBPK software (Pksim/MOBI, SimCyp, Gastroplus) and applications for implementing QSP models.
  • Proficiency in R, Matlab, Python or similar programming language is required
  • Experience with one or more population modelling software is desirable (Monolix, NONMEM or similar)
  • You know how to work independently and within a team. Your reactivity allow you to handle short delay and high pressure in competitive projects.
  • You have a good written and oral communication in English.

 

What’s in it for you?

You will be part of a fast growing and amazing company. You will get all the support you need to make your job successful. At Galapagos we aim to recruit the best people, who stand out among their peers, with integrity and excellent interpersonal and organizational skills. Our employees are the strength behind Galapagos, a highly motivated team, eager to maintain Galapagos’ leading position and achieve breakthroughs in pharmaceutical research. Galapagos offers a competitive remuneration package and a dynamic work environment.

We are Galapagos: together we can make it happen…!