Head of Pre-Clinical ADME Leaders - Romainville, FR (or Leiden, NL)

Job description

Pleased to meet you, we are Galapagos, a dynamic fast growing biotech company with offices in Europe, in Belgium (Mechelen), France (Romainville), the Netherlands (Leiden), Switzerland (Basel) and in the US (Boston).

We’re in the business of changing lives. In our quest to discover and develop life-improving medicines we go where no one has ever gone before. In every challenge we face, we see new opportunities. We want to challenge the impossible. We need thought leaders and rapid thinkers, entrepreneurs in spirit and status quo-fighters. Collaborative innovators and perseverant idealists, we need the best-in-class. In other words, we need you: The ‘make-it-happeners’.

We are looking for a Head of Pre-Clinical ADME Leaders - Romainville, FR (or Leiden, NL)

Scope of the job

The Head of ADME Leaders is accountable for all Pharmacokinetics/ Pharmacodynamics (PK/PD) and Absorption, Distribution, Metabolism and Excretion (ADME) in all Pre-Clinical development phases of Galapagos’ drug candidates. In addition, the Head of ADME Leaders is responsible in supporting the Discovery Departments regarding Toxicokinetics and Metabolism aspects.

The Head of ADME Leaders leads the Pre-Clinical ADME Leaders according to senior management guidance. The Head of ADME Leaders ensures the ADME strategy for each of the development projects across the entire development portfolio is determined, translated into Pre-Clinical development plans and executed.

Your role

  • The Head of ADME Leaders trains, mentors and/or inspires the Pre-Clinical ADME Leaders.
  • Set out the most efficient organizational structure in the Pre-Clinical ADME Leaders team, managing roles to cover ADME responsibilities and determining and managing the team budgetary needs
  • Manage staff recruitment, team building, mentoring and coaching
  • Provide the PK/PD and ADME expertise (training and internal expert network) needed to drive the decisions
  • Assign ADME Leaders to development projects based on needs across the portfolio in coordination with the Head of PCD
  • Collaborate with multidisciplinary team members and other subject matter experts to drive the development of Pre-Clinical drug candidates ensuring the integration of nonclinical and early clinical findings with planned clinical programs
  • Select and manage vendors delivering PK/PD and ADME services, in line with Galapagos’ operational model
  • Manage and maintain a network of external specialists that can be called in by ADME Leaders when specific Pre-Clinical challenges arise
  • Execute the PCD elements in the Master Audit plan and CAPA plans in close collaboration with the Quality Management department
  • Identify and implement the necessary PCD Information Systems

Job requirements

Who you are?

  • The successful candidate has at least a PhD degree in-life science, with at least 15 years of experience within the life-science / pharmaceutical industry
  • You have an excellent background in ADME
  • You show proficiency in drug development strategies regarding the non-clinical safety evaluation, especially late phases
  • You have already some people management experience
  • You should be able to organize and plan multiple priorities, and have the ability to coordinate and collaborate having excellent interpersonal and organizational skills
  • You should have excellent communication skills, together with being fluent in English (oral and in writing). French is a plus.

What’s in it for you ?

You will be part of a fast growing and amazing company. As ‘make-it-happener’ you will get all the support you need to make your job successful. At Galapagos we aim to recruit the best people, who stand out among their peers, with integrity and excellent interpersonal and organizational skills. Our employees are the strength behind Galapagos, a highly motivated team, eager to maintain Galapagos’ leading position and achieve breakthroughs in pharmaceutical research. Galapagos offers a competitive remuneration package and a dynamic work environment.

We are Galapagos : together we can make it happen…!